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KMID : 0882420140870040484
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Korean Journal of Medicine
2014 Volume.87 No. 4 p.484 ~ p.490
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A Case Report of Recurrent Malignant Paraganglioma with Lung and Spine Metastasis that Occurred Sixteen Years after Primary Tumor Excision
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Moon Eul-Sun
Min Hye-Sook
Jung Chang-Ho
Choi Jong-Hyun
Kim Jun-Suk
Yoo Hye-Jin
Choi Sang-Yong
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Abstract
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Paragangliomas are rare tumors that arise from the extra-adrenal chromaffin cells, and malignancy is defined by the presence of metastases to sites that normally lack chromaffin tissue. The main therapeutic targets are tumor reduction and control of excessive catecholamine secretion. Currently, the adjuvant therapy to surgery is radiotherapy treatment using high-dose MIBG; chemotherapy is currently evolving. We report herein a case of malignant paraganglioma with lung and spine metastasis that occurred 16 years after primary tumor excision and was treated with high dose MIBG radiotherapy and chemotherapy.
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KEYWORD
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Malignant paraganglioma, Lung metastasis, Spine metastasis, Metaiodobenzylguanidine, Chemotherapy
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